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Nonsteroidal anti-inflammatory drugs with follow-up x-ray in 6 months
3%
53/1979
Intramedullary nailing
1%
18/1979
Intravenous antibiotics
Radiation therapy
50/1979
Preoperative chemotherapy, wide resection, and postoperative chemotherapy
92%
1829/1979
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The clinical presentation, radiographs, and pathology are consistent with osteosarcoma. The radiographs show a mixed lytic/blastic destructive lesion. The pathology specimen shows pleomorphic osteoblastic cells and lacey osteoid. Therefore, the answer to this question is neo-adjuvant chemo and wide resection. In the referenced study by Bacci et al they reported that the “The five-year disease-free survival and overall survival rates were 60.7% (limb salvage) and 68.5% (amputation), respectively, with no significant difference between patients undergoing amputation and those undergoing resection.”
4.4
(23)
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