The research of Rafael J. Sierra, M.D., involves clinical trials in hip and knee arthroplasty, prospective and retrospective clinical research in hip preservation surgery, and the diagnosis and management of femoral head osteonecrosis. Dr. Sierra also focuses on prevention of complications associated with primary and revision hip arthroplasty. He investigates the biomechanics of periprosthetic fractures, the improvement of function with soft tissue procedures of the abductor mechanism and failure modes of dual mobility implants. Dr. Sierra has multicenter trials investigating how to improve the perioperative management of people with knee arthroplasty and the treatment of periprosthetic infection.