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Review Question - QID 211486

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QID 211486 (Type "211486" in App Search)
A 42-year-old obese male with a BMI of 41 sustains a closed left transverse midshaft tibia fracture. He subsequently undergoes reamed intramedullary fixation 36 hours following the injury. After surgery, the patient is prescribed 800 mg ibuprofen twice daily as well as oxycodone for pain control. The patient also endorses smoking cigarettes, 1 pack per day, for 20 years. Which of the following factors places this patient at highest risk for developing a non-union?