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Review Question - QID 218184

QID 218184 (Type "218184" in App Search)
A 72-year-old female presents to clinic three months after a total knee arthroplasty. There is concerns that she is developing a prosthetic joint infection (PJI). Her incision is well-healed without drainage or dehiscence. Based on the 2018 Diagnostic Criteria for PJI defined by Parvizi and associates, what preoperative lab abnormalities in isolation would most strongly suggest an infected prosthetic joint?