As an orthopedic clinician-scientist with broad-based training in orthopedic surgery, biomechanics and biochemistry, Matthew P. Abdel, M.D., is interested in studying clinically relevant pathologies while considering the functional impact on patients. Dr. Abdel's laboratory is focused on investigating the genetic expression profiles of people predisposed to joint contractures (arthrofibrosis), osteolysis and deep periprosthetic infections through the use of both animal models and human trials. In addition, he is interested in studying the epidemiology and best treatment modalities for patients with periprosthetic infections and fractures. As a clinician, Dr. Abdel's expertise is in complex revision total hip and knee procedures for the treatment of arthrofibrosis, osteolysis, oncologic resections, periprosthetic infections and periprosthetic fractures. As such, his research is directly translational to his clinical practice, reinforcing the clinician-scientist role.