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Osteomyelitis - Adult
Posted: Nov 20 2022
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Stages of Biofilm Formation | Microbiology Lectures | Bacterial Biofilms | Basic Science Series

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Stages of Biofilm Formation | Microbiology Lectures | Bacterial Biofilms | Basic Science Series

A typical Biofilm is composed of a population of microorganisms in which microbial cells are attached to each other and also attached to a solid surface.
Stages of Biofilm formation:
1. Initial attachment. this stage starts with the attachment of free-floating cells to a solid surface.
2. Irreversible attachment. In this stage, if the initial attachment process is successful bacteria use cell adhesion structures to attach tightly to the surface.
3. Initial maturation of biofilm: Micro and macro colony formation
4. Final maturation of biofilm: at this stage bacterial cells start producing a very high amount of exopolysaccharide material in their surroundings.
5. Dispersion or detachment stage: At this stage, the cells detach themselves from bacterial biofilms to look for a new areas for the formation of new biofilms.

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