summary Congenital Amputations are upper extremity amputations that are most commonly associated with amniotic band constriction. Diagnosis is made clinically with a variable location of amputation. Treatment depends on the level of amputation and may be addressed with prosthesis placement as necessary. Epidemiology Incidence rare Anatomic location transradial is the most common location Etiology Pathophysiology due to failure of formation Genetics no clear genetic involvement Risk factors amniotic band constriction Associated conditions typically not associated with systemic conditions Presentation Symptoms usually painless functional deficits Physical exam varies depending on location of amputation Imaging Radiographs AP and lateral of affected extremity Treatment Nonoperative prosthesis placement indications fitting with passive terminal prosthesis recommended at the age of 6 months ("fit when they sit")